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PLoS ONE 5:e10074

A dysbiotic microbiome can deconjugate estrogen in the gut and recirculate it

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Also, optical/physical radiations (ultraviolet, visible light, infrared) as well as systemic drugs (chloroquine, fluphenazine, physostigmine, imatinib) and topical drugs (imiquimod, long-term use of topical steroid) have been reported as vitiligo promoters (Harris 2017

The most common condition associated with folate deficiency is affective disorders, such as MDD

doi: 10.2478/v10007-012-0005-2 56 KahalyGJRiedlMKnigJDianaTSchomburgL