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Rauf A, Badoni H, Abu-Izneid T, Olatunde A, Rahman MM, Painuli S et al (2022) Neuroinflammatory markers: key indicators in the pathology of neurodegenerative diseases

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Adjunct drugs such as catechol-O-methyltransferase (COMT) and monoamine oxidase-B (MAO-B) inhibitors lack specificity to the central nervous system (CNS), have poor BBB permeability, and result in systemic side effects 15,16

Quick conversions: 1.0 mg = 6 units , 1.5 mg = 9 units , and 2.0 mg = 12 units

10.1093/mutage/gew030 49 Diez-PascualA

The results directly indicated that the targeting motif RGD-binding peptide RGD-GHK almost totally suppressed the collagenase (MMP-1) expression, resisted H 2 O 2 -induced COL-1 degradation, and simultaneously promoted collagen synthesis compared with GHK alone for cell anti-aging performance