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Research published in PubMed demonstrates that DSIPs influence on the GABAergic system contributes significantly to its sleep-promoting properties

Plantone D, Primiano G, Manco C, Locci S, Servidei S, De Stefano N

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209 Excessive hydrophobicity may lead to strong hemolytic toxicity, which may be caused by the self-binding of the peptides that may impede the peptides pass through prokaryotic cell membranes without hindering their passage through eukaryotic cell membranes

Additionally, red or dark red discoloration of the urine may occur, indicating hematuria as a result of inflammation of the bladder mucosa