However, with the passage of time, the motor function deteriorated in most of the groups (Grade 1.2 to 2.3 at 16 weeks post SNR) with the exception of Groups 7 and 8 (Grade 3.0) that received G-CSF and Dihexa, respectively, to the gastrocnemius muscle (Table 2)
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Physiological Reviews
200 Bellevue, WA 98006, USA * Correspondence: Loren Pickart Academic Editors: Luis Martinez and Michael Fossel Received: June 8, 2018 | Accepted: August 2, 2018 | Published: August 16, 2018 OBM Geriatrics 2018 , Volume 2, Issue 3 doi:10.21926/obm.geriatr.1803009 Recommended citation: Pickart L, Margolina A
As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively