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Heres a breakdown of the two main mechanisms: 1

9,10 The cGSTs are divided into seven subtypes according to similarities in amino-acid sequence, different structure of genes, and immunological cross-reactivity

System X(c) (-)/GSH/GPX4 axis: an important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

Emerging roles of ferroptosis in the tumor immune landscape: from danger signals to anti-tumor immunity

Alterations of lower respiratory tract microbiome and short-chain fatty acids in different segments in lung cancer: a multiomics analysis

Existing therapeutic strategies mainly focus on regulating homocysteine levels, with limited effective interventions targeting methionine itself