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Miller JD, et al

Like BPC-157, its marketed for muscle, tendon and ligament recovery

4 A 2025 mechanistic study using RAMP1/RAMP3 knockout mice demonstrated this dependence directly: cagrilintide activated area postrema neurons and reduced body weight in wild-type animals but had essentially no effect in mice lacking these receptors, pinning its action to the AMY and AMY subtypes in the hindbrain

If baseline levels are intact but receptor efficiency has degraded