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[DOI] [PMC free article] [PubMed] 78.Shahmiri M, Enciso M, Adda CG, Smith BJ, Perugini MA, Mechler A

GHK-Cu (Copper Tripeptide): Barrier Rebuilder GHK-Cu is a copper-binding tripeptide (glycyl-L-histidyl-L-lysine) that occurs naturally in human plasma and drops significantly with age

Oxidative stress homeostasis in grapevine ( Vitis vinifera L.)

It is determined by the pharmacokinetics of each specific peptide, the therapeutic goal, and the cycle structure prescribed

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Notably, tyrosinase possesses two copper ions, i.e., CuA and CuBcoordinate with six histidine (His) residues in the conserved catalytic pocket 14,15 , and are critically required to exhibit both types of enzymatic activities 6,16