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Glutamine administration in patients undergoing cardiac surgery and the influence on blood glutathione levels

Sample SJ, Hao Z, Wilson AP, Muir P

Neuroprotection in the Central Nervous System Glutathione (GSH) plays a vital neuroprotective role in the central nervous system (CNS), primarily by regulating redox homeostasis, detoxifying electrophilic compounds, and modulating excitotoxic signaling pathways

Queval et al., 2011)

The pharmacokinetic barrier has recently been overcome with the synthesis of the orally active, blood-brain barrierpermeable analog N-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide (dihexa)

elife 7