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The functional distinction between the enzymes terminal extensions is further demonstrated by structural analyses: the N-terminal extension seems to maximize substrate binding in alkaline environments through better cavity interactions and structural stabilization, whereas the C-terminal extension improves acid tolerance

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The study also revealed that NRF2 mediates nicotine-induced ferroptosis

Decreased total antioxidant capacity and increased oxidative stress in passive smoker infants and their mothers

October 10, 2024