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This was a recommendation both in the James Lind Alliance Priority Setting Partnership which PAS initiated and funded and in the NICE Guideline on B12 Deficiency which PAS initiated

& Churg, J

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Basic amino acids confer a positive net charge [155]

6,7,20 There is an intimate connection between abnormal GST expression and multidrug resistance, unequivocally implicating GST, a member of the GST family in tumor-drug resistance