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5OCQA, a known dietary precursor of this metabolite (3methoxycinnamic acid4sulfate), has been shown in clinical studies to reduce diastolic and systolic blood pressure, and beverages containing acylquinic acids have produced an acute improvement in flowmediated dilatation, implying that many people who drink such beverages regularly may gain at least a modest health benefit long term (Rubi et al., 2021)

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In human retinal pigment epithelium cells, bilberry anthocyanins have been demonstrated to modulate the oxidative stress-protective enzymes glutathione S-transferase-pi and heme oxygenase-1 (HO-1) [269]

Results appear with consistent daily use