While the cells treated with Ru(II)-OH or NP2 in a 1% O 2 atmosphere were confluent and alive, the cell treated with NP4 had a strongly reduced cell population and a mixture of living and dead cells comparable to the treatment with these nanoparticles in a 21% O 2 atmosphere (Fig
Furthermore, Nalm6 cells lacking FANCB were significantly sensitive to GSH inhibition even in the absence of FA, which might be a consequence of an increase in endogenous free FA, overall suggesting that GSH supply might be fundamental for Fanconi Anaemia patients (Fig
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Cerebral blood flow obstruction is the primary pathological mechanism of IS, while brain damage persists and continues to progress during reperfusion (78, 79)
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