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Progres en Urologie

177 SHANKs were first implicated in ASD by studies on PhelanMcDermid syndrome, 200,201 a neurodevelopmental disorder caused by 22q13.3 deletion, and are deleted in almost all reported PhelanMcDermid syndrome cases

GHK-Cu represents an alternative for cases that fail standard care

These injections are not a quick fix but can play a supportive role in a larger plan

For hair growth specifically, combining topical GHK-Cu with microneedling is supported by the strongest evidence as shown in the 2025 Kuceki study which achieved 26.5% regrowth with this combination approach

Additionally, there was a negative linear relationship between the number of days with headache and serum vitamin D levels in patients with migraine (104)