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Finally, an imbalance in GSSG:GSH ratio induced ER stress and dependency on the ER-associated degradation pathway, driven by a shift in protein disulfide isomerases towards their oxidized forms

Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesis

Eur J Endocrinol 143: 639-647 Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, et al

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While its effect on the oxidative stress markers seems to be influenced even at low dosages, the higher doses may ensure more rapid response