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However, only ~ 50% patients with opioid-induced constipation exhibit satisfactory response to PAMORA-based clinical management strategies targeting MORs in the enteric nervous system, and we observed that naloxegol could only partially alleviate morphine-induced constipation

10.1136/gutjnl-2023-329685 Gut 171 KoprichJ

The traditional model of medicine is just get a diagnosis, write a prescription

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The physical strain often leads to injuries, performance issues, and the need for guidance on recovery

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