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A large share of the published literature originates from one research group, using a comparatively narrow set of models

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Calcium phosphate, cellulose, stearic acid (vegetable source), food-grade coating (hypromellose, titanium dioxide, polydextrose, talc, maltodextrin, medium chain triglycerides), silicon dioxide, and magnesium stearate (vegetable source)

Loren Pickart first isolated it in 1973 while studying compounds involved in tissue repair and regeneration