glutathione inhibitor Targeted inhibition of NOX activation and biosynthesis for Structural Biology Platform Facilitates Discovery

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F.TymianskiM

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Adams, P.C

This mass spectrometric behavior agrees with and justifies several independent lines of evidence which derive from chemical, biochemical and pharmacological studies

The induction of mitochondrial damage and oxidative stress through the combined use of an inhibitor of glutamine metabolism and an inhibitor of lipid metabolism (pimozide) resulted in GBM cell death