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Ghrelin Gene and Ghrelin Production Sites The Ghrelin gene is made up of six exons and three introns, located on chromosome 3, at the 3p25-2 locus, although the first exon made up of 20 bp is a non-coding exon (exon 0 of 20 bp) (27)

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Moreover, they can inhibit protein expression related to the NLRP3/ASC/caspase-1 signaling pathway, consequently impacting immune inflammation and exerting antidepressant effects

Yilmaz, G., Srer, H., Inan, L

Funding This work is supported by the National Natural Science Foundation of China (grant number 81570623 and 8197058