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Dec 21: The FDA on Thursday signed off on the first and only self-administered treatment for polyneuropathy in hereditary transthyretin-mediated amyloidosis (hATTR-PN): AstraZeneca and Ionis eplontersen, now to be known as Wainua

[DOI] [PubMed] [Google Scholar] 269.Kang Y-J, Jo J-O, Cho M-K, Yu H-S, Leem S-H, Song KS, et al

Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

Engineered nanodelivery systems to improve DNA vaccine technologies

Venlafaxine and desvenlafaxine have been found to reduce the frequency and severity of hot flashes

UCB causes mitochondrial ROS production, which consequently causes activating p38 and p53 downstream, ultimately leading to the increased regulation of the pro-apoptotic protein Bax and the decreased regulation of the anti-apoptotic protein Bcl-2 and phosphorylation of Bcl-xL/Bcl-2 associated death promoter (Bad) (83), thus causing apoptosis