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Most common side effects of GHSs The potential side effects of GH secretagogues depend on the specific compound and may include: local reactions at the injection site fractal flushing nausea and digestive issues increased appetite and weight gain elevated prolactin levels elevated cortisol levels insulin resistance water retention All GHSs except Ibutamoren are applied via injections, which can lead to local adverse reactions such as pain, swelling, and redness at the injection site

Alpha-fetoprotein (AFP) is a glycoprotein that is highly expressed in embryonic liver and in hepatic progenitor cells (hepatoblasts) (Usynin and Panin, 2008

Precautions and Professional Use Only a licensed healthcare provider should administer the injection

Elevated N-methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform

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doi: 10.1093/nar/gks1219 37 ReichardtN.DuncanS