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It is normal for the solution to darken slightly over time under refrigeration, particularly due to the riboflavin content

For Hereditary B12 Malabsorption If you suffer from Imerslund-Grasbeck disease, your vitamin B12 malabsorption will be treated with hydroxocobalamin injected into the muscle at a dose of 10 mg per day for 10 days followed by monthly injections for life

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Prostaglandins interact directly with local pain receptors

Its important to check how well the treatment is working during this time