Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: potential role of metal dyshomeostasis in Crohns disease
1 Introduction The glutathione peroxidase family (GPX) is a family of antioxidant enzymes that are an essential class of selenoenzymes in mammals ( 2 O 2 or organic hydroperoxides to water or corresponding alcohols, thereby mitigating their toxicity ( In mammals, GPX works with superoxide dismutase and catalase to form an enzymatic antioxidant system that reduces reactive oxygen species (ROS) and limits their toxicity
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