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Notably, no significant increases in markers of inflammation or oxidative stress were observed in the liver of Gclc L-KO mice compared to Gclc WT mice (Fig

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Similar results were obtained with mRNA expression of MMP-2 ( P =0.01), stromal-derived factor-1 (SDF-1) ( P =0.01), tumor growth factor (TGF)- ( P =0.001) and poly-(ADP-ribose) polymerase (PARP) that occurs in response to DNA damage ( P =0.001) (Figure 5b)

Cantoni O, Zito E, Guidarelli A, et al

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Shelf life is 18 months from manufacture date when stored properly