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A 2021 study involving patients with diarrhea-predominant IBS found that 12 weeks of clinoptilolite supplementation significantly enhanced intestinal wall integrity and drastically reduced the patients' need for "rescue medications" to manage their severe gastrointestinal distress, underscoring its clinical utility in managing chronic gut dysfunction

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Lopez A, Harada K, Chen HC, Bhutani MS, Weston B, Lee JH, Maru DM, Chin FW, Rogers JE, Thomas I, Amlashi FG, Blum-Murphy MA, Rice DC , Zhao M, Hofstetter WL, Nguyen Q, Ajani JA