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The pathophysiology of elevated vitamin B12 in clinical practice Significance of elevated cobalamin (vitamin B12) levels in blood Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease

In respiratory disease, cellular damage and injury is mediated by an increased oxidant burden and/or decreased antioxidant defenses

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Hypervitaminosis B12 in commercial broiler chickens

Berberine can also regulate cAMP response element binding protein (CREB) and brain-derived neurotrophic factor (BDNF) to further regulate synaptic plasticity (Shaker et al., 2021)