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Vitamin B12 contributes to Energy yielding metabolism Functioning of the nervous system Red blood cell formation Homocysteine metabolism Psychological function Functioning of the immune system Vitamin B12 also plays a role in the process of cell division and the reduction of tiredness and fatigue

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This vascular remodeling decreases elasticity, heightening peripheral resistance and blood pressure [186, 187]

Tirzepatide suppresses this compensatory ghrelin increase through central nervous system effects, breaking the typical hunger rebound cycle

The clinical evaluation before prescribing exists precisely to identify these contraindications