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Mark Haupt, MD, shares insights from his work in research, academia, and the pharmaceutical industry

229, 238, 245, 246 Of 26 total patients, 20 (77%) had complete pain relief and one was moderately improved

Genistein administration induced Nrf2 enhancement by activation/phosphorylation of keap1, sirt1, MAPK-ERK1/2, PKC, and estrogen receptor in other cells or tissues, such as: hippocampal tissue, hypothalamic paraventricular nucleus, ovary, and Caco-2 cells [131, 135,136,137]

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doi:10.3109/15563659309000395