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However, lifestyle factors can disrupt this balance, leading to oxidative stress and diminished health

Catalase deficiency is linked with many diseases, such as neurological disorders (Alzheimers disease, Parkinsons disease, schizophrenia, and bipolar disorder), metabolic diseases (diabetes I and II, hypertension, insulin resistance), and cancer, anemia, and asthma

Therefore, enhanced iron uptake and decreased iron output will increase the vulnerability of cells to oxidative harm and ferroptosis

Nat Rev Endocrinol 8(3):160171