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Then, rats started to drink excessively, then to eat and repeatedly drink water for a period of a few minutes

Weight loss with CagriSema reached 15.6% versus 5.1% with semaglutide alone and 8.1% with cagrilintide alone, demonstrating clear superiority of the combination over either component

However, human evidence remains limited

TNF- production decreased significantly in the BV group compared to the control group, whereas IL-1 levels remained constant (Lee JaeDong et al., 2004)

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While menstrual irregularities were not systematically reported as adverse events in published results, the substantial weight loss achieved (approximately 20.9% with the 15 mg dose) would be expected to influence reproductive hormone dynamics in premenopausal women based on established weight loss physiology