found that base modification could considerably reduce the hepatotoxicity of gapmer ASO, 245 providing insights for developing new gapmer ASOs
Furthermore, the incorporation of maleimide introduced a reactive group for targeting peptides [32]
Additionally, while this review primarily focuses on the mechanisms through which natural products regulate osteogenesisangiogenesis coupling, it is important to note that gut hormones such as GLP-1 and GIP may also play critical roles in bone homeostasis
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[DOI] [PubMed] [Google Scholar] 112.Fujii H., Doi H., Ko T., Fukuma T., Kadono T., Asaeda K., Kobayashi R., Nakano T., Doi T., Nakatsugawa Y., et al