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Seek urgent medical attention (via NHS 111 or 999 in an emergency) if you experience severe or persistent abdominal pain, persistent vomiting, signs of dehydration (such as dizziness, reduced urination, or extreme thirst), or symptoms suggestive of low blood sugar (such as shakiness, sweating, or confusion)

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Hemorrhoids and fissures share overlapping pathology, but extrapolating from fissure data to hemorrhoids is mechanistically plausible, not clinically validated

A study found that giving 1000 mcg of B12 intramuscularly is common