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7(5):e2412780 Turana Y, Tengkawan J, Chia YC, Hoshide S, Shin J, Chen C et al (2019) Hypertension and dementia: a comprehensive review from the HOPE Asia network

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Studies have suggested that Nrf2 is activated in the joints of arthritic mice and patients with rheumatoid arthritis, whereas Nrf2 deficiency is associated with accelerated arthritis development 44,45 , suggesting that Nrf2 might be a potential therapeutic target for OA