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Molecular pathways: tumor cells co-opt the brain-specific metabolism gene CPT1C to promote survival

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Valproic Acid Metabolism The complex metabolism of valproic acid leads to much of its associated toxicity

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After being exported from cells by multidrug resistance protein, extracellular and circulating GSH is hydrolyzed by -glutamyltransferase (GGT), an enzyme localized at the outer surface of cell membranes, to produce glutamic acid and cysteinylglycine (Cys-Gly) (15, 16)

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