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Results The optimization, when applied to age paired rats, both nulligravid and pregnant, shows that pregnancy induces, at seventeen d of pregnancy, an increase of both reactive oxygen substance concentration in red blood cells and membrane glutathione peroxidase activity

Details of the PCR primers used are provided in Table S2

But its not quite that simple

ROS levels are lower, and telomeres are longer, in oocytes from young females (68 weeks of age) than in those from reproductively aged female mice (4248 weeks of age) (Yamada-Fukunaga et al., 2013)

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Low molecular weight thiols, such glutathione, have been shown to upregulate the nitric oxide (NO) pathway