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Whilst timing of supplementation is less critical than consistency, factors such as formulation type, food intake, and underlying gastrointestinal health significantly influence absorption efficiency

Thus, BPC 157 does not act as a serotonin substrate

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Plausible degradation pathways include: Serum aminopeptidases (cleaving from the N-terminus) Endopeptidases (internal bond cleavage) Hepatic uptake and degradation Renal clearance (though direct renal excretion of intact peptide of this size is typically limited) Whether BPC-157 generates active metabolites i.e., smaller peptide fragments that retain biological activity is not established in the public literature