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Mental illnesses including depression and seasonal affective disorder often correlate with suboptimal B12 levels , particularly during winter months when natural Vitamin D3 synthesis decreases

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Intriguingly, -1 is not the only Th2 inducing glycoprotein secreted by schistosome eggs, as another glycoprotein, Omega1 (-1), a T2 ribonuclease, has shown to be the primary method by which the eggs induce a Th2 response (181)

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