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In an oncogenic context, the IGF family regulates a number of biological processes such as cancer cell proliferation, apoptosis, metabolism and protein synthesis, which are closely associated with the activation of PI3K/AKT signaling, which subsequently promotes the transcription of downstream pro-oncogenic target genes such as c-Myc and HIF-1 (77)

Use of aprotinin in extrapleural pneumonectomy: effect on hemostasis and incidence of complications

That is fine

Amer MA, Ghattas MH, Abo-Elmatty DM, Abou-El-Ela SH

The anonymous collection of discarded blood samples from SCD children undergoing chronic transfusion was classified as exempt by the Institutional Review Board at Augusta University and did not require informed consent

Nihon Eiseigaku Zasshi