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Vitamin B12 is essential to maintain nervous system integrity and promote red blood cell synthesis

For this reason, it might be important to either lose weight or have a fat reduction treatment in this area, as a part of your treatment (although that will not remove existing pigmentation)

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Fat loss typically accelerates, body composition shifts become visible, and stubborn areas begin responding

General subcutaneous injection at distant sites like the abdomen can still provide systemic benefits, just potentially with a slower onset for the specific shoulder condition