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Instead, the selected literature was analyzed and synthesized thematically, with studies grouped according to biological pathways (e.g., monoaminergic modulation, neurotrophic signaling, HPA-axis regulation, neuroinflammation, oxidative stress, and mitochondrial function) and level of evidence (preclinical versus clinical)

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Precision and individualization are essential

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9 Conclusion and prospects NP-based cancer treatment has emerged as a revolutionary approach in precision oncology, addressing a range of issues related to drug release profiles, target selectivity, and control of cellular signaling pathways linked to cancer

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