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OATP1A1 has been found in cell types other than the proximal tubules, such as hepatocytes, which use the GSH electrochemical gradient to drive organic anion uptake [129]

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28,29,516 Specifically, IGF-1 treatment results in increases in synaptic protein levels and activation of signalling pathway proteins and enhances cortical excitatory synaptic transmission and dendritic spine density