Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age
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Eur J Pharmacol 794:127134 Wakefield RJ, Balint PV, Szkudlarek M, Filippucci E, Backhaus M, DAgostino MA, Sanchez EN, Iagnocco A, Schmidt WA, Bruyn GA, Kane D, OConnor PJ, Manger B, Joshua F, Koski J, Grassi W, Lassere MN, Swen N, Kainberger F, Klauser A, Ostergaard M, Brown AK, Machold KP, Conaghan PG, Group OSI (2005) Musculoskeletal ultrasound including definitions for ultrasonographic pathology
Although a modest decrease in viability was observed after 24 h at 26C, this difference did not reach statistical significance (Welchs t-test, p = 0.0808)
Tyrosinase is an enzyme that catalyzes the biosynthesis of melanin which is a culprit for skin darkening
47-55, (2018) (PubMed)
