Serine (and glycine) can also be oxidized to oxalate (see also the Lipolysis and the Oxidation of Fatty Acids page) through a series of reactions proceeding to 3-hydroxypyruvate which involves transamination of pyruvate
Clinical research has found that women with increased 2-hydroxylation of estrogen towards inactive metabolites have more lean body mass and less body fat than those women with estrogen not guided down that healthy path.2 Clinical work also shows that encouraging increased 2-hydroxylation may lower systolic blood pressure in women post menopause, so bolstering proper estrogen metabolism has far-reaching effects.3 Additionally, insufficient 2-hydroxy metabolism is associated with reduced bone mass, issues with blood sugar, and increased potential for hormone-related cancers.2,4 So, how do you support it
Having significant antioxidant properties
It works by neutralizing free radicals, which are unstable molecules that can damage cells, proteins, and DNA
At the same time, it must not have adverse effects on the biological system, such as causing immune responses, toxic reactions, etc
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