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Cell 186 , 53285346 (2023)

TCM uses A

doi:10.1210/jc.2014-2222 43

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Cardiovascular Safety The SELECT trial evaluating cardiovascular outcomes in patients with obesity and established cardiovascular disease demonstrated that serious adverse events were actually lower with semaglutide versus placebo (33.4% vs 36.4%), primarily driven by fewer cardiac disorders (11.5% vs 13.5%)

As indicated above, one of the first characterized differences was the dependence on P i for activity