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LJ: Funding acquisition, Project administration, Supervision, Writing review and editing

Insufficient testing No data to show they are safe or effective: Most of these substances are not clinically tested on humans, and none of them have undergone the extensive trials required to gain FDA approval as a medicine

Many manufacturers like Bella advertise their products on social media platforms such as RedNote and TikTok, posting trays of vials set to pop music and using language borrowed from beauty influencer marketing, including so-called POV skits

The oral LD50 of lidocaine HCl in non-fasted female rats is 459 (346 to 773) mg/kg (as the salt) and 214 (159 to 324) mg/kg (as the salt) in fasted female rats

BPC 157 in Gastrointestinal Research Models