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Similarly, GPx4 and GPx7 were found to be overexpressed in HCC tissues and their levels correlate with the malignancy grade [314]

297 Additionally, Hcy levels are significantly elevated in HD patients, indicating that Hcy may contribute to neurodegeneration in HD

The development of antioxidants that can reduce oxidative damage to specific biomolecules without interfering with the physiological functions of ROS has become a research focus

Bax oligomerization is associated with the formation of openings in the OMM to allow the release of cytochrome c and other IMS proteins into the cytosol, and hence Bax oligomerization is considered a critical regulatory point in cell death (Youle and Strasser, 2008)

Studies have also shown that drinking yerba mate tea can naturally improve serum lipid levels, thereby lowering cholesterol levels

Arch Toxicol 82(5):273299 Mats JM, Segura JA, Alonso FJ, Mrquez J (2012a) Oxidative stress in apoptosis and cancer: an update