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Otic agents and/or other pharmaceutical agents disclosed herein are optionally incorporated within controlled release particles, lipid complexes, liposomes, nanoparticles, microspheres, nanocapsules or other agents which enhance or facilitate the localized delivery of the otic agent

TB-500 represents a synthetic fragment of thymosin beta-4 that retains functional motifs involved in actin cytoskeleton regulation and cellular migration processes

doi: 10.3389/fneur.2020.00828 362 HulensMRasschaertRVansantGStalmansIBruyninckxFDankaertsW

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The therapeutic protocol typically involves initial intensive injections followed by maintenance schedules based on individual blood levels and clinical response