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Other antidepressants are used off-label to support cessation efforts by addressing mood-related symptoms associated with quitting

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Another neuromodulation method is transcranial direct current stimulation (tDCS), which provides a weaker electrical current over a longer duration to the brain, modulating neural firing without producing stimulation of neurons (177)

Nicotine is addictive because it acts on brain receptors to release dopamine and other neurotransmitters that produce pleasure and mood changes, leading to physical and psychological dependence

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