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The DiGeorge syndrome , also called velocardiofacial or 22q11.2 deletion syndrome (22q11.2DS), is caused by a hemizygous microdeletion (1.53 Mb) on chromosome 22 DiGeorge syndrome The prevalence rate of this condition is ~1 in 4000 [356]

Thus, it needs to be cleared out quickly to prevent cell and DNA damage, which can lead to cancerous mutations.[ref] Two well-studied genetic variants have different ways of reaching the same endpoint: ~ an alcohol dehydrogenase (ADH1B) variant that speeds up the conversion to acetaldehyde, thus creating a buildup of acetaldehyde ~ an acetaldehyde dehydrogenase (ALDH2) variant that slows down the conversion from acetaldehyde to acetic acid, again creating a buildup of acetaldehyde

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While Vitamin B12 is widely available, the setting in which you receive your injection matters for both safety and effectiveness