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Furthermore, in a distinct study focusing on CFS, an impressive 70% of patients reported significant symptom alleviation, with the treatment presenting no major adverse effects [67]

doi: 10.1111/jgh.14292

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In addition, emerging work suggests that specific microbiota-derived secondary bile acids can directly suppress colonic inflammation through epithelial cGMP-PKG signaling (with downstream restraint of mTORC1), providing a mechanistic link between bile acid remodeling and mucosal protection 151

The profiles are the result of cell lines treated with GHK at 1 micromolar which is around the concentration where many of GHKs cellular effects occur [15]