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372,373 Moreover, the -face of Cu I -coordinated His ligand interacts with residues in the second coordination shell including nearly invariant Tyr and Glu residues that are energetically linked to Cu I -mediated allosteric inhibition of DNA binding, suggesting a path for allosteric connectivity

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References to clinical trials and published research throughout this description are provided for informational and research context only and do not constitute medical claims or endorsements of any therapeutic application of this product.